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Results for "

Gram-negative anaerobic

" in MedChemExpress (MCE) Product Catalog:

40

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4

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5

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0159
    Balofloxacin

    Q-35

    		 Bacterial Antibiotic Infection
    Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections .
    Balofloxacin
  • HY-B1118
    Secnidazole

    RP-14539; PM-185184

    		 Parasite Antibiotic Bacterial Infection
    Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .
    Secnidazole
  • HY-125496
    A201A

    		Antibiotic Bacterial Infection
    A201A is a aminoacylnucleoside antibiotic with antibacterial activities. A201A is highly effective against Gram-positive and most Gram-negative anaerobic bacteria. A201A inhibits tRNA accommodation during translation .
    A201A
  • HY-B0159A
    Balofloxacin dihydrate

    Q-35 dihydrate

    		 Bacterial Antibiotic Infection
    Balofloxacin dihydrate (Q-35 dihydrate) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin dihydrate can be used for the research of respiratory, intestinal, and urinary tract infections .
    Balofloxacin dihydrate
  • HY-B1118A
    Secnidazole hemihydrate

    RP-14539 hemihydrate; PM-185184 hemihydrate

    		 Antibiotic Bacterial Parasite Infection
    Secnidazole (RP-14539) hemihydrate is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole hemihydrate, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole hemihydrate has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole hemihydrate can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .
    Secnidazole hemihydrate
  • HY-N7102
    Ceftiofur
    3 Publications Verification

    		 Bacterial Antibiotic Infection
    Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive and gram-negative, aerobic and anaerobic bacteria encountered by domestic animals .
    Ceftiofur
  • HY-B0026
    Ceftiofur hydrochloride

    		Bacterial Antibiotic Infection
    Ceftiofur hydrochloride is a semisynthetic antibiotic, with activity against various gram-positive and gram-negative, aerobic and anaerobic bacteria encountered by domestic animals .
    Ceftiofur hydrochloride
  • HY-116228
    Cadrofloxacin

    Caderofloxacin; CS-940

    		 Bacterial Infection
    Cadrofloxacin (Caderofloxacin; CS-940), a orally active fluoroquinolone, is effective against aerobic/anaerobic Gram-positive and Gram-negative bacteria. Cadrofloxacin can be used for the research of infectious diseases .
    Cadrofloxacin
  • HY-B1484
    Moxalactam sodium salt
    1 Publications Verification

    Latamoxef sodium; Lamoxactam sodium; LY-127935 sodium

    		 Beta-lactamase Bacterial Antibiotic Infection
    Moxalactam (Latamoxef) sodium salt is a synthetic oxa-β-lactam antibiotic. Moxalactam sodium salt has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Moxalactam sodium salt inhibits production of β-lactamases .
    Moxalactam sodium salt
  • HY-B1484A
    Moxalactam

    Latamoxef; Lamoxactam; LY-127935
    Moxalactam (Latamoxef) is a synthetic oxa-β-lactam antibiotic. Moxalactam has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Moxalactam inhibits production of β-lactamases .
    Moxalactam
  • HY-14865C
    Omadacycline hydrochloride
    Maximum Cited Publications
    19 Publications Verification

    PTK0796 hydrochloride; Amadacycline hydrochloride

    		 Bacterial Antibiotic Infection
    Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
    Omadacycline hydrochloride
  • HY-14865
    Omadacycline
    Maximum Cited Publications
    19 Publications Verification

    PTK 0796; Amadacycline

    		 Bacterial Antibiotic Infection
    Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
    Omadacycline
  • HY-14865A
    Omadacycline mesylate

    PTK 0796 mesylate; Amadacycline mesylate

    		 Bacterial Antibiotic Infection
    Omadacycline (PTK 0796) mesylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline mesylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline mesylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline mesylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
    Omadacycline mesylate
  • HY-14865B
    Omadacycline tosylate
    Maximum Cited Publications
    19 Publications Verification

    PTK 0796 tosylate; Amadacycline tosylate

    		 Bacterial Antibiotic Infection
    Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
    Omadacycline tosylate
  • HY-B1825
    Cefoxitin
    4 Publications Verification

    		 Antibiotic Bacterial Infection Cancer
    Cefoxitin, a β-lactam antibiotic, is a broad-spectrum, second-generation cephalosporin. Cefoxitin has a broad spectrum antibacterial activity which includes anaerobic as well as Gram-positive and Gram-negative aerobic bacteria .
    Cefoxitin
  • HY-B1369
    Imipenem monohydrate
    15+ Cited Publications

    N-Formimidoyl thienamycin monohydrate; MK0787 monohydrate
    Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
    Imipenem monohydrate
  • HY-138094
    N-(2-Hydroxyethyl)oxamic acid

    		Drug Metabolite Infection
    N-(2-hydroxyethyl)-oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria .
    N-(2-Hydroxyethyl)oxamic acid
  • HY-B0479
    Thiamphenicol

    Thiophenicol; Dextrosulphenidol

    		 Beta-lactamase Bacterial Antibiotic Infection
    Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
    Thiamphenicol
  • HY-B1369A
    Imipenem

    N-Formimidoyl thienamycin; MK0787

    		 Antibiotic Bacterial Infection
    Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
    Imipenem
  • HY-B0395
    Sitafloxacin

    DU6859a

    		 Bacterial Antibiotic Infection
    Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection .
    Sitafloxacin
  • HY-B0536
    Clinafloxacin

    AM-1091; CI-960; PD 127391

    		 Bacterial Antibiotic Infection
    Clinafloxacin (AM 1091) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro . Clinafloxacin is against DNA gyrase and topoisomerase IV of S. aureus with IC50 values of 0.92 µg/ml and 1.62 µg/ml, respectively .
    Clinafloxacin
  • HY-B0536A
    Clinafloxacin hydrochloride

    AM 1091 hydrochloride; CI 960 hydrochloride; PD127391 hydrochloride

    		 Bacterial Antibiotic Infection
    Clinafloxacin hydrochloride (AM 1091 hydrochloride) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro . Clinafloxacin hydrochloride is against DNA gyrase and topoisomerase IV of S. aureus with IC50 values of 0.92 µg/ml and 1.62 µg/ml, respectively .
    Clinafloxacin hydrochloride
  • HY-B0479S
    Thiamphenicol-d3

    Thiophenicol-d3; Dextrosulphenidol-d3

    		 Isotope-Labeled Compounds Bacterial Antibiotic Infection
    Thiamphenicol-d3 is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria)[1][2].
    Thiamphenicol-d3
  • HY-B1923S
    Piperacillin-d5

    Pipracil-d5

    		 Antibiotic Bacterial Infection
    Piperacillin-d5 is deuterium labeled Piperacillin. Piperacillin is kind of semisynthetic penicillins. Piperacillin has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Piperacillin has shown greater activity against β-lactamase-producing organisms than the other penicillins[1].
    Piperacillin-d5
  • HY-B0395B
    Sitafloxacin monohydrate

    DU6859a monohydrate

    		 Bacterial Antibiotic Infection
    Sitafloxacin (DU6859a) monohydrate is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin monohydrate shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin monohydrate can be used for the research of respiratory tract infection and urinary tract infection .
    Sitafloxacin monohydrate
  • HY-B0395A
    Sitafloxacin hydrochloride

    DU6859a hydrochloride

    		 Antibiotic Bacterial Infection
    Sitafloxacin (DU6859a) hydrochloride is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin hydrochloride shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin hydrochloride can be used for the research of respiratory tract infection and urinary tract infection .
    Sitafloxacin hydrochloride
  • HY-B0479R
    Thiamphenicol (Standard)

    Thiophenicol (Standard); Dextrosulphenidol (Standard)

    		 Beta-lactamase Bacterial Antibiotic Infection
    Thiamphenicol (Standard) is the analytical standard of Thiamphenicol. This product is intended for research and analytical applications. Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
    Thiamphenicol (Standard)
  • HY-113829
    Valnemulin

    		Antibiotic Bacterial Infection Inflammation/Immunology
    Valnemulin is an orally active broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria, anaerobic bacteria, Mycoplasma, and Spirochetes. Valnemulin ameliorates enteric diseases, acute polyarthritis and enzootic pneumonia in pigs . Valnemulin exhibits anti-inflammatory efficacy against lipopolysaccharide (HY-D1056)-induced lung injury .
    Valnemulin
  • HY-B1257
    Cefmetazole sodium

    Sodium cefmetazole

    		 Bacterial Antibiotic Infection
    Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
    Cefmetazole sodium
  • HY-B1595
    Cefmetazole

    CS 1170
    Cefmetazole (CS 1170) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative and anaerobic bacteria. Cefmetazole binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
    Cefmetazole
  • HY-B0479S1
    Thiamphenicol-d3-1

    Thiophenicol-d3-1; Dextrosulphenidol-d3-1

    		 Isotope-Labeled Compounds Infection
    Thiamphenicol-d3-1 (Thiophenicol-d3-1; Dextrosulphenidol-d3-1) is the deuterium-labeled Thiamphenicol (HY-B0479) . Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
    Thiamphenicol-d3-1
  • HY-A0170
    Trovafloxacin
    1 Publications Verification
    Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 .
    Trovafloxacin
  • HY-103399
    Trovafloxacin mesylate
    1 Publications Verification

    		 Bacterial Topoisomerase Antibiotic Infection
    Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 .
    Trovafloxacin mesylate
  • HY-B1118S2
    Secnidazole-d4

    RP-14539-d4; PM-185184-d4

    		 Bacterial Parasite Antibiotic Infection
    Secnidazole-d4 is the deuterium labeled Secnidazole[1]. Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis[1][2][3].
    Secnidazole-d4
  • HY-N8461
    Reuterin

    3-Hydroxypropionaldehyde; 3-Hydroxypropanal

    		 Bacterial Infection
    Reuterin is a broad-spectrum antimicrobial agent active against Gram positive and Gram negative bacteria, as well as yeasts, moulds and protozoa. Reuterin is produced by specific strains of Lactobacillus reuteri during anaerobic metabolism of glycerol. Reuterin also demonstrates potent antimicrobial activity against a broad panel of human and poultry meat campylobacter spp. Isolates .
    Reuterin
  • HY-13678
    Meropenem
    10+ Cited Publications

    SM 7338

    		 Penicillin-binding protein (PBP) Bacterial Antibiotic Infection Cancer
    Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
    Meropenem
  • HY-13678A
    Meropenem trihydrate
    10+ Cited Publications

    SM 7338 trihydrate

    		 Penicillin-binding protein (PBP) Bacterial Antibiotic Infection Cancer
    Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
    Meropenem trihydrate
  • HY-13678S1
    Meropenem-d6-1

    SM 7338-d6-1

    		 Bacterial Antibiotic Infection
    Meropenem-d6-1 (SM 7338-d6-1) is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
    Meropenem-d6-1
  • HY-16487
    Temafloxacin

    TMFX; TA-167 free acid; A-62254 free acid

    		 Bacterial Antibiotic Infection
    Temafloxacin (TMFX) is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin is well tolerated in lower respiratory and genitourinary tract infections .
    Temafloxacin
  • HY-113595
    Temafloxacin hydrochloride

    TMFX hydrochloride; TA-167; A-62254

    		 Antibiotic Bacterial Infection
    Temafloxacin (TMFX) hydrochloride is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin hydrochloride is well tolerated in lower respiratory and genitourinary tract infections .
    Temafloxacin hydrochloride

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